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Initially diagnosed June 4, 2009 Invasive Ductal Carcinoma Stage II,Grade II tumor size: 2-3 cm node positive ER/PR postive HER2 Neu - negative Current Diagnosis: Metastatic Invasive Ductal Carcinoma Grade 3 Mets: Scalp/skin, Liver, Spine, Bone ER/PR + HER2/NEU -

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Wednesday, October 23, 2013

Preliminary Biopsy Reports Showed Up

I logged into MD Anderson this morning and the preliminary biopsy reports were posted.  There was only one thing, the subtype, that was included that was not told to me previously.  No ER/PR or HER2 status were indicated, but it’s most likely what they call “Triple Negative” which means ER/PR negative and HER2 negative based on the subtype.  Here is the text from the initial biopsy.  I’m sure there will be more information in the future indicating ER/PR and HER status more specifically.

 

SPECIMEN SOURCE

A. Soft tissue, right superior ear, FNA

GROSS DESCRIPTION

0.66 x 0.66 x 0.49 cm nodule

Immediate assessment for specimen adequacy was made (×1).

DIAGNOSIS

POORLY DIFFERENTIATED ADENOCARCINOMA (see comment)

COMMENT

Immunostain performed on a smear show the tumor cells to be positive for pan-cytokeratin. The finding supports the above diagnosis.

Control is appropriate.

 

 

Adenocarcinoma is simply the grouping invasive ductal carcinoma falls under.  It will probably be more clearly defined on the final report.  Testing positive for Pan-Cytokeratin, from my research, appears to indicate the tumor is a basal-like cell and most likely triple negative.  Here is a link for you to understand better what basal-like breast cancer subtype means:

 

 

http://ww5.komen.org/BreastCancer/SubtypesofBreastCancer.html

 

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